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Botanical

St. John's Wort

St. John's Wort (Hypericum perforatum) is a flowering plant whose aerial parts contain hypericin, hyperforin and flavonoids. It is mostly studied for low mood.

Also listed as St. John's Wort Extract, St. John's Wort Aerial Parts, St. John's Wort Aerial Parts Extract, St. John's Wort Glycerite Liquid Extract

Stress & MoodSleepCognitionEssential Health

Which interactions matter?

St. John’s wort can weaken birth control pills, warfarin, cyclosporine and some seizure, HIV and cancer medicines. Combining it with serotonin-affecting antidepressants can cause serious adverse effects. A medication review with a clinician or pharmacist is important before use. 1

What else needs consideration?

NCCIH warns about sun-related skin reactions and possible harm during pregnancy or breastfeeding. Diarrhea, dizziness, restlessness and sleep problems can also occur. Depression warrants professional assessment rather than delaying care to try a supplement. 1

For information, not individual medical advice. Ingredient studies do not establish the effectiveness of these products.

Sources