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Amino acid

Agmatine

Agmatine is a compound the body forms from the amino acid arginine. It is mainly studied for its role in nerve signaling.

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What adverse effects were reported?

An initial dose-escalation study reported diarrhea and nausea in three participants at the highest dose. 1

What does long-term follow-up establish?

Two authors monitored their own use of 2.67 g/day for four to five years and reported normal clinical and laboratory assessments. Such self-observation cannot establish population-wide safety or reliably exclude uncommon harms. 2

For information, not individual medical advice. Ingredient studies do not establish the effectiveness of these products.

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