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Botanical

Berberine

Berberine is a yellow plant alkaloid found in barberry, goldenseal and Oregon grape, and is mostly studied for blood sugar.

Also listed as Berberine Extract 10:1, Dihydroberberine, berberine hcl, berberine hydrochloride

Weight ManagementCardiovascularGut HealthOrgan Function

Which adverse effects matter?

Reported effects include nausea, abdominal pain, bloating, constipation and diarrhea. Berberine can interact with medicines, including cyclosporine. 1

Who should avoid it?

The Verbraucherzentrale relays ANSES advice against use in children, pregnancy, breastfeeding, diabetes, and liver or heart disease. 2

Is there an established safe dose?

The 2026 EFSA draft assessment cited by the Verbraucherzentrale could not establish a safe daily dose because of safety concerns and data gaps. 2

For information, not individual medical advice. Ingredient studies do not establish the effectiveness of these products.

Sources

  2. Berberin zum Abnehmen? Verbraucherzentrale