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Botanical

Devil's Claw

Devil's claw (Harpagophytum procumbens) is a plant from southern Africa whose tuberous secondary roots are used as a herbal medicine.

Also listed as Grapple Plant, Duiwelsklou, Wood Spider, Harpagophytum Procumbens

Bone & JointGut HealthLongevity

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

Joint ComfortBone & JointModerateBNo linked study
Gut healthSmallCNo linked study
Oxidative stressLongevitySmallCNo linked study
InflammationSmallCNo linked study
Every rating with its studiesGrouped by health goal, with the publications behind each rating

What is devil’s claw?

The medicinal material is the tuberous secondary root of Harpagophytum procumbens or H. zeyheri. EMA recognizes traditional use for minor joint pain, bloating and temporary appetite loss. 1

Why people take it

Bone & Joint26.1%
Immune Support19.3%
Essential Health18.5%
Detox9%
Longevity7.4%
Stress & Mood7.4%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Questions people ask

Are all extracts dosed alike?

No. EMA lists preparation-specific amounts, so milligrams of different extracts are not interchangeable. 2

When should joint pain be assessed?

EMA advises medical assessment for swollen or red joints, fever, worsening symptoms, or pain persisting beyond four weeks of use. 2

Sources