EGCG
EGCG (epigallocatechin gallate) is the most abundant catechin in green tea and belongs to the polyphenols, a large group of plant compounds.
The main concern is the liver
EFSA found that supplemental doses of 800 mg EGCG daily or more increased liver enzymes in clinical trials, a sign of possible liver injury. EFSA could not identify a safe supplemental dose. 1
Which warnings apply in the EU?
Required warnings say not to consume the covered extracts on an empty stomach, alongside other green-tea products on the same day, during pregnancy or breastfeeding, or under age 18. 2
Medicine interactions also matter
Green tea extract can reduce blood levels of atorvastatin. NCCIH also describes interactions involving nadolol and raloxifene, and advises discussing supplements with a clinician when taking medicines. 3
For information, not individual medical advice. Ingredient studies do not establish the effectiveness of these products.
Sources
- Scientific opinion on the safety of green tea catechins EFSA Journal, 2018
- Commission Regulation (EU) 2022/2340: green tea extracts containing EGCG European Commission, 2022
- Green Tea NCCIH