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Botanical

EGCG

EGCG (epigallocatechin gallate) is the most abundant catechin in green tea and belongs to the polyphenols, a large group of plant compounds.

The main concern is the liver

EFSA found that supplemental doses of 800 mg EGCG daily or more increased liver enzymes in clinical trials, a sign of possible liver injury. EFSA could not identify a safe supplemental dose. 1

Which warnings apply in the EU?

Required warnings say not to consume the covered extracts on an empty stomach, alongside other green-tea products on the same day, during pregnancy or breastfeeding, or under age 18. 2

Medicine interactions also matter

Green tea extract can reduce blood levels of atorvastatin. NCCIH also describes interactions involving nadolol and raloxifene, and advises discussing supplements with a clinician when taking medicines. 3

For information, not individual medical advice. Ingredient studies do not establish the effectiveness of these products.

Sources