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Botanical

Neem

Neem is Azadirachta indica, an evergreen tree of the mahogany family from the Indian subcontinent. Its leaves, bark and seed oil are used in Ayurveda.

Also listed as Azadirachta indica, Neem Extract, Organic Neem, Organic Neem Extract

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Swallowed oil can cause severe poisoning

LiverTox describes rare severe poisoning after neem-oil ingestion, particularly in young children. Vomiting and increasing drowsiness can progress to metabolic acidosis, coma and liver dysfunction; deaths have occurred. A traditional history does not remove this risk. 1

Skin reactions and possible interactions

Topical neem can cause contact dermatitis. Neem extract also inhibited drug-metabolizing enzymes in laboratory experiments, but the significance for medicine interactions in people is unknown. 2

For information, not individual medical advice. Ingredient studies do not establish the effectiveness of these products.

Sources

  1. Margosa Oil LiverTox, 2020
  2. Neem Memorial Sloan Kettering Cancer Center