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Botanical

Neem

Neem is Azadirachta indica, an evergreen tree of the mahogany family from the Indian subcontinent. Its leaves, bark and seed oil are used in Ayurveda.

Also listed as Azadirachta indica, Neem Extract, Organic Neem, Organic Neem Extract

Can it help blood sugar?

A randomized trial enrolled 80 adults with type 2 diabetes who were already using metformin. An aqueous leaf-and-twig extract improved fasting and after-meal glucose, HbA1c and insulin resistance over 12 weeks compared with placebo. This encouraging adjunct-treatment result does not test replacing metformin. 1

Blood sugarToo little evidence

One small, short trial supports further study of this particular extract. 1

Cholesterol balanceToo little evidence

The same trial found no effect on the lipid profile. 1

Why do other claims remain interesting?

MSK describes a small bark-extract study that reduced stomach acid secretion, and laboratory work on cancer cells. Those are distinct lines of research; the cell findings do not establish a cancer treatment in people. 2

Questions outside this review

This profile does not assess skin aging, immune support or liver-health benefits.

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Weight Management1 effect

Blood sugarWeight ManagementModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Immune Support1 effect

Immune SupportModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Organ Function1 effect

Liver healthOrgan FunctionSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Hair & Skin2 effects

Skin InflammationHair & SkinSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Anti-aging SkinHair & SkinSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Longevity1 effect

Oxidative stressLongevitySmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Gut Health1 effect

Gut healthSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cardiovascular1 effect

Cholesterol balanceCardiovascularSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Sources

  1. Neem Memorial Sloan Kettering Cancer Center