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Botanical

Mangosteen

Mangosteen (Garcinia mangostana) is a tropical fruit. Its rind contains xanthones, compounds studied in the laboratory for anti-inflammatory activity.

Also listed as Garcinia mangostana L., Purple mangosteen, Queen of Fruits, Queen of Tropical Fruits

LongevityImmune SupportWeight ManagementHair & SkinGut Health

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

Oxidative stressLongevityModerateBNo linked study
Immune SupportModerateBNo linked study
Blood sugarWeight ManagementSmallBNo linked study
Cellular health & agingLongevitySmallCNo linked study
Skin InflammationHair & SkinSmallCNo linked study
Microbiome healthGut HealthSmallCNo linked study
All 8 rated effectsGrouped by health goal, with the publications behind each rating

What is mangosteen?

Mangosteen, Garcinia mangostana, is a tropical fruit. Its rind contains xanthones, compounds studied for anti-inflammatory activity in laboratory experiments. Those experiments do not establish a treatment benefit in people. 1

Why people take it

Immune Support21.2%
Essential Health16%
Energy14.9%
Detox8.8%
Gut Health8.6%
Fitness4.9%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Questions people ask

Does it lower blood sugar?

Glucose did not improve in the small pilot trial. 2

Is fruit the same as an extract?

The trial tested a standardized capsule, not ordinary fruit servings. 2

Is natural necessarily safe?

MSK reports a serious adverse-event case; a case report cannot establish how often harm occurs. 1

Sources

  1. Mangosteen Memorial Sloan Kettering Cancer Center