Andrographis
Andrographis paniculata is an Asian medicinal herb whose leaves are used in traditional medicine. Andrographolide is considered its main active compound.
Also listed as Andrographis Extract, Andrographis Seed, Andrographis Seed Extract, Andrographis Powder
What it is studied for
The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.
What is andrographis?
Andrographis paniculata is an Asian medicinal herb whose leaves and other above-ground parts are used in traditional medicine. Andrographolide and related compounds are considered important active constituents. Most of the clinical evidence discussed here concerns respiratory symptoms. 1
Why are researchers interested in inflammation?
Laboratory and animal experiments show that andrographolide can influence inflammatory signaling, including NF-κB, a regulator of inflammatory gene activity. This provides a mechanism to investigate, but does not establish that an oral herbal product treats chronic inflammatory disease. 2
Key studies
The most recent publications linked to Andrographis's ratings.
Why people take it
SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.
Questions people ask
Does previous tolerance mean it is safe next time?
No. TGA reports that severe reactions can occur after earlier uneventful use. 3
Do cold studies prove stronger immunity?
They primarily assess symptom relief during acute illness, not general immune protection. 4
Is it suitable while breastfeeding?
The EMA assessment did not establish safety during breastfeeding; it reported that this had not been studied. 5