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CDP-Choline

CDP-choline (citicoline) is a compound the body makes from choline and cytidine. It is a precursor of phosphatidylcholine, a building block of cell membranes.

Also listed as Citicholine, Cytidine Diphosphocholine, Citicoline, CDPCholine

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

Brain FogCognitionModerateBNo linked study
Focus And AttentionCognitionModerateBNo linked study
MemoryCognitionModerateBNo linked study
Oxidative stressLongevityModerateBNo linked study
Mental EnergyCognitionSmallCNo linked study
Every rating with its studiesGrouped by health goal, with the publications behind each rating

Why people take it

Cognition26.6%
Energy23.9%
Stress & Mood14%
Longevity10.3%
Fitness9.6%
Essential Health5.9%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Sources

  1. SuppCo · CDP-Choline nutrient profile