Fructose
Fructose is a simple sugar found mainly in fruit and honey. Table sugar is half fructose and half glucose.
What it is studied for
The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.
What is fructose?
Fructose is a simple sugar found primarily in fruit. Its absorption in the intestine and its subsequent processing in the body are different steps, which helps explain why fructose malabsorption and hereditary fructose intolerance are different conditions. 1
Why people take it
SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.
Questions people ask
Is fruit juice counted as free sugar?
Yes. EFSA includes sugars in fruit juice in this category. 2
Is fructose a weight-loss ingredient?
The feeding-trial review does not support a weight-loss advantage from calorie-matched substitution. 3
Does a lower glucose response make it healthier?
The substitution studies establish a short-term response, not a general health advantage. 4
Sources
- Hereditary fructose intolerance MedlinePlus Genetics
- Effect of fructose on body weight in controlled feeding trials: a systematic review and meta-analysis Annals of Internal Medicine, 2012
- Fructose replacement of glucose or sucrose in food or beverages lowers postprandial glucose and insulin without raising triglycerides: a systematic review and meta-analysis American Journal of Clinical Nutrition, 2017