Skip to content
DE
Botanical

Hesperetin

Hesperetin is a flavanone, a type of flavonoid from citrus fruit. The body forms it from hesperidin during digestion.

CardiovascularLongevityImmune SupportCognition

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

Cholesterol balanceCardiovascularModerateBNo linked study
Oxidative stressLongevityModerateBNo linked study
InflammationModerateBNo linked study
Immune SupportModerateBNo linked study
Blood pressureCardiovascularSmallBNo linked study
MemoryCognitionSmallCNo linked study
Every rating with its studiesGrouped by health goal, with the publications behind each rating

How is hesperetin different from hesperidin?

Hesperetin is the aglycone of hesperidin: the same underlying flavonoid without its attached sugar group. Both occur in the citrus research literature, but their names are not interchangeable when judging a supplement trial. 1

Why people take it

Immune Support25%
Essential Health20.8%
Energy12.5%
Inflammation8.3%
Cardiovascular8.3%
Men's Hormones8.3%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Questions people ask

Is hesperetin the same as hesperidin?

No. Hesperetin lacks the sugar group attached to hesperidin. 1

Does the circulation research prove it lowers blood pressure?

The cited human experiments studied acute peripheral blood flow, not sustained treatment of hypertension. 2 3

Is there an established daily dose here?

The single-dose experiments do not establish a long-term regimen for general health. 2 3

Sources