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Botanical

Horse Chestnut

Horse chestnut, Aesculus hippocastanum, is a tree whose seed extracts are used in herbal medicine. Escin is their main active constituent.

Also listed as Aesculus hippocastanum, Conker tree, Rosskastanie, venostasin

Does it help with chronic venous insufficiency?

A Cochrane review of 17 randomized trials found short-term improvements in symptoms such as leg pain, swelling, and itching with standardized extracts. Trials lasted 2–16 weeks. The reviewers called for larger, more rigorous trials, so the evidence is most useful for short-term symptom relief rather than a claim of curing damaged veins. 1 2

How does Europe assess it?

EMA recognizes certain oral seed extracts as having well-established medicinal use for chronic venous insufficiency. Its conclusions for minor venous discomfort and bruises rely on traditional use, a different level of evidence. 3

What about other uses?

NCCIH notes small amounts of research for varicocele-related male infertility and irritable bowel syndrome, but insufficient information for firm conclusions. Those questions remain open rather than established indications. 2

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Longevity1 effect

Oxidative stressLongevityModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Hair & Skin1 effect

Skin InflammationHair & SkinSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Cardiovascular1 effect

Blood pressureCardiovascularSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Bone & Joint1 effect

Joint ComfortBone & JointSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Stress & Mood1 effect

Chronic StressStress & MoodNo effectFNo linked study

No study is linked to this rating.

Rated by SuppCoEvidence record

Other effects1 effect

InflammationSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Sources

  1. Horse Chestnut National Center for Complementary and Integrative Health