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Phosphatidylserine

Phosphatidylserine is a phospholipid found in cell membranes, especially in the brain. Supplements are usually made from soy or sunflower lecithin.

Also listed as PS, Phosphatidyl Serine

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What do short trials tell us?

Health Canada’s assessment of soy-derived PS found reassuring short-term trial data and derived a recommended maximum daily intake of 300 mg for its use as a supplemental food ingredient. This Canadian assessment does not cover PS from other sources and is not a dose proven to prevent dementia. 1

What remains uncertain?

Long-term use is poorly studied. The Alzheimer’s Drug Discovery Foundation notes possible blood-pressure effects and bleeding concerns, and recommends discussing a new supplement with a physician. 2

For information, not individual medical advice. Ingredient studies do not establish the effectiveness of these products.

Sources

  2. Phosphatidylserine Alzheimer’s Drug Discovery Foundation, 2023