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Botanical

Reishi

Reishi, or lingzhi, is a woody mushroom of the genus Ganoderma with a long history in traditional Chinese and Japanese medicine.

Also listed as Lingzhi, Yeongji, Mannamtake, Mushroom Of Immortality

Immune SupportLongevityOrgan FunctionStress & MoodCognition

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

Immune SupportModerateBNo linked study
InflammationModerateBNo linked study
Oxidative stressLongevityModerateBNo linked study
Liver healthOrgan FunctionModerateBNo linked study
StressStress & MoodSmallCNo linked study
Mental EnergyCognitionSmallCNo linked study
All 10 rated effectsGrouped by health goal, with the publications behind each rating

What makes reishi interesting?

Reishi, Ganoderma lucidum, contains beta-glucan polysaccharides and triterpenes. Laboratory and animal studies suggest immune-modulating and anti-inflammatory activity. These findings explain the research interest without establishing a clinical benefit on their own. 1

Why people take it

Immune Support22.4%
Energy17.2%
Stress & Mood11%
Cognition9.5%
Longevity8.9%
Essential Health8.5%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Questions people ask

Can reishi replace cancer treatment?

The Cochrane review does not support first-line treatment with reishi, and long-term survival was not measured. 2

What dose lowered blood pressure?

The analyzed trials using 1.4 to 3 g daily did not show a significant blood-pressure benefit. 3

Can reishi interfere with a cancer blood test?

MSK reports that spore products can raise CA72-4. The treatment team needs to know about their use when interpreting results. 1

Sources

  1. Reishi Mushroom Memorial Sloan Kettering Cancer Center