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Botanical

Reishi

Reishi, or lingzhi, is a woody mushroom of the genus Ganoderma with a long history in traditional Chinese and Japanese medicine.

Also listed as Lingzhi, Yeongji, Mannamtake, Mushroom Of Immortality

What does immune support mean in the trials?

A Cochrane review included five trials with 373 cancer patients. Some immune-cell measures and quality-of-life scores improved, but study quality was poor and no trial measured long-term survival. These are preliminary findings in cancer care, not evidence that healthy people will catch fewer infections. 1

Immune SupportToo little evidence

Immune-marker changes warrant further study but do not establish general infection protection. 1

Does it improve blood pressure?

A separate Cochrane review could analyze three trials with 157 people with type 2 diabetes. Across 12 to 16 weeks, it found no significant blood-pressure benefit and no convincing improvement in glucose or cholesterol. 2

Blood pressureNot supported

The analyzed diabetes trials did not improve blood pressure. 2

What does newer research add?

A 2025 synthesis of 17 trials with 971 participants also found no significant overall blood-pressure or inflammatory-marker effect. An antioxidant enzyme, glutathione peroxidase, increased, but several other oxidative-stress markers did not change. All outcomes had very low-certainty evidence. 3

Oxidative stressMixed

One antioxidant-enzyme finding was favorable, while other markers were unchanged; clinical relevance remains uncertain. 3

Other questions

This profile does not evaluate sleep, stress, mental energy or liver-health benefits.

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Immune Support1 effect

Immune SupportModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Longevity1 effect

Oxidative stressLongevityModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Organ Function1 effect

Liver healthOrgan FunctionModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Stress & Mood3 effects

StressStress & MoodSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Chronic StressStress & MoodSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Acute StressStress & MoodSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cognition1 effect

Mental EnergyCognitionSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cardiovascular1 effect

Blood pressureCardiovascularSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Sleep1 effect

Sleep qualitySleepSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Other effects1 effect

InflammationModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Sources