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Enzyme

Cellulase

Cellulase is a group of enzymes that break down cellulose, the main fiber in plant cell walls. Humans do not make it; supplement cellulase usually comes from fungi.

Gut Health

A promising result for a blend

A 40-person trial in functional dyspepsia, persistent upper-abdominal symptoms, tested a five-enzyme blend containing cellulase, amylase, protease, lactase and lipase. At 50 mg three times daily for 60 days, symptom scores improved versus placebo. The authors worked for the manufacturer. 1

Bloating & gas reliefToo little evidence

Blend results do not isolate cellulase. 1

Which ingredient helped?

A narrative review found encouraging results for mixed enzymes in meal-related digestive symptoms. However, the trials did not separate the contributions of individual enzymes. Whether cellulase itself improves bloating remains an open question, not a finding of no effect. 2

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Gut Health4 effects

Microbiome healthGut HealthSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Bloating & gas reliefGut HealthSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Gut healthSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Digestive sensitivityGut HealthNo effectFNo linked study

No study is linked to this rating.

Rated by SuppCoEvidence record

Other effects2 effects

ConstipationNo effectFNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

DiarrheaNo effectFNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Sources