Guduchi

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

Immune SupportModerateBNo linked study

Liver healthOrgan FunctionModerateBNo linked study

Gut healthModerateBNo linked study

Oxidative stressLongevityModerateBNo linked study

Cholesterol balanceCardiovascularModerateBNo linked study

Blood sugarWeight ManagementModerateBNo linked study

All 10 rated effectsGrouped by health goal, with the publications behind each rating

What is guduchi?

Guduchi, also called giloy, usually refers to Tinospora cordifolia, a climbing plant used in Ayurvedic medicine. Extracts may come from leaves, roots or bark. Its history of use includes liver and immune claims, but LiverTox now classifies it as a well-established cause of clinically apparent liver injury. 1

Why is the immune claim complicated?

Tinospora contains multiple compounds, and the constituent responsible for liver injury has not been identified. Clinical features suggest an immune-mediated mechanism. A substance influencing immune activity can therefore raise a safety question as well as a therapeutic research question. 1

Why people take it

Immune Support25.2%

Detox19.3%

Essential Health12.6%

Gut Health11.1%

Stress & Mood8.9%

Energy5.9%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Questions people ask

Is guduchi established as a liver-protective supplement?

No. LiverTox identifies Tinospora as a well-established cause of liver injury despite traditional liver-protection claims. 1

Does the allergy result deserve further study?

Yes, the symptom improvement is a specific human finding. It needs to be considered alongside the subsequent serious safety evidence. 1 2

Do case reports reveal how often harm occurs?

No. The case series describes affected patients without measuring all exposed users, so it cannot estimate an incidence rate. 3