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Botanical

Japanese Knotweed

Japanese knotweed (Polygonum cuspidatum) is a fast-growing perennial plant from East Asia. Its root is a main commercial source of resveratrol.

Also listed as Hu zhang, Polygonum cuspidatum, Bambou Japonais, Japanese Knotwood

What changed in the human trial?

Twenty healthy adults received placebo or knotweed extract for six weeks. Several inflammation and oxidative-stress measurements improved with the extract. These were blood and cell measurements, not tests of pain relief, infection prevention or longer life. The findings justify further research without answering those everyday health questions. 1

InflammationToo little evidence

A small trial found favorable marker changes; clinical benefits remain uncertain. 1

Oxidative stressToo little evidence

Laboratory measurements improved in healthy adults in one short trial. 1

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Longevity1 effect

Oxidative stressLongevityModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Immune Support2 effects

Immune SupportModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Immune responseImmune SupportSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cardiovascular2 effects

Blood pressureCardiovascularSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Cholesterol balanceCardiovascularSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Bone & Joint1 effect

Joint MobilityBone & JointSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Gut Health1 effect

Gut healthSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Hair & Skin1 effect

Skin InflammationHair & SkinSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Other effects1 effect

InflammationSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Sources