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Enzyme

Peptidase

Peptidase is the group name for enzymes that split proteins and peptides into smaller pieces and amino acids. They are common in digestive enzyme blends.

Do enzyme supplements help indigestion?

A 2023 randomized trial enrolled 120 adults with functional dyspepsia, persistent upper-digestive symptoms without a clear cause after assessment. A fungal multienzyme blend, 200 mg per capsule twice daily for two months, improved symptom-related quality of life, pain and sleep scores versus placebo. 1

This is useful preliminary evidence for the tested blend. It cannot identify which enzyme contributed or establish the same result for an isolated peptidase. The study reported no side effects, but its two-month duration cannot resolve long-term safety. 1

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Gut Health4 effects

Bloating & gas reliefGut HealthSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Microbiome healthGut HealthSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Gut healthSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Digestive sensitivityGut HealthSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Other effects2 effects

ConstipationSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

DiarrheaSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Sources