Enzyme
Protease
Proteases are enzymes that break proteins down into smaller peptides and amino acids. Supplements come from plants such as pineapple and papaya, from microbes or from animal pancreas.
What it is studied for
The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.
Every rating with its studiesGrouped by health goal, with the publications behind each rating
Why people take it
Essential Health20.5%
Gut Health18.9%
Immune Support17.5%
Energy12.4%
Detox11.9%
Fitness3.8%
SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.