Folic Acidand Mood Support.
Evidence gradeC
ImpactSmall
Confidencemedium
Imported rating. This grade comes from SuppCo and has not been independently reviewed. It describes research, not a product, and it is not medical advice.
The rating
- Direction
- Favourable
- Rated by
- SuppCo
- Observed
- 28 September 2026
Studies behind it
The effects of folic acid supplementation on depression in adults: a systematic review and meta-analysis of randomized controlled trialsParniyan Khalili · Nutrition & Food Science2022Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCTE. J. de Koning · Nutrients2016