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Fatty acid

Pentadecanoic Acid

Pentadecanoic acid, or C15:0, is an odd-chain saturated fatty acid found in small amounts in dairy fat and some fish and plants.

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

Oxidative stressLongevityModerateBNo linked study
InflammationModerateBNo linked study
Cholesterol balanceCardiovascularModerateBNo linked study
Blood sugarWeight ManagementModerateBNo linked study
Gut healthModerateBNo linked study
MetabolismWeight ManagementSmallCNo linked study
All 7 rated effectsGrouped by health goal, with the publications behind each rating

What is pentadecanoic acid?

Pentadecanoic acid, or C15:0, is an odd-chain saturated fatty acid found in small amounts in dairy fat and some fish and plants. Laboratory and animal work has explored effects on inflammation and mitochondrial function, the machinery that helps cells produce energy. 1

Why people take it

Longevity25%
Essential Health25%
Cognition16.7%
Organ Function16.7%
Inflammation8.3%
Cardiovascular8.3%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Questions people ask

Does a high C15:0 blood level prove protection from diabetes?

No. The cohort evidence shows an association, not proof that raising the level prevents disease. 2

Is the essential-fatty-acid claim settled?

The cited paper presents it as a hypothesis requiring further research. 1

Does dairy intake affect the blood marker?

Yes. A controlled crossover study found higher C15:0 in cholesteryl esters after a dairy-rich diet. 3

Does flavoring approval establish supplement safety?

No. JECFA’s conclusion refers to current exposure as a flavoring agent. 4

Sources