Alfalfa
Alfalfa, Medicago sativa, is a legume grown mainly as animal feed. Its leaves and sprouts contain saponins, estrogen-like isoflavonoids and vitamin K.
Also listed as Organic Alfalfa Grass, Alfalfa Extract, Alfalfa Leaf Extract, Alfalfa Leaf
What it is studied for
The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.
What is alfalfa?
Alfalfa, Medicago sativa, contains saponins, estrogen-like isoflavonoids, vitamin K and L-canavanine in its leaves and sprouts. These constituents help explain both research interest and precautions. 1
How might it affect cholesterol?
Laboratory work suggests that alfalfa saponins and fiber can bind cholesterol. This mechanism is a reason to investigate the plant, not proof that a capsule improves cardiovascular health. 2
Why people take it
SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.
Questions people ask
Is it a proven cholesterol treatment?
No. The small seed study is promising but does not establish reliable effectiveness. 3
Does cooking address all supplement risks?
BfR’s heating advice concerns foodborne infection; it does not establish supplement safety. 4
Can alfalfa cause digestive symptoms?
Diarrhea, gas and abdominal discomfort have been reported. 2