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Gamma Oryzanol

Gamma oryzanol is a mixture of plant compounds called sterol ferulates, obtained from rice bran oil.

Also listed as γ-Oryzanol

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

InflammationModerateBNo linked study
Cholesterol balanceCardiovascularModerateBNo linked study
Oxidative stressLongevityModerateBNo linked study
Gut healthSmallCNo linked study
Bone densityBone & JointSmallCNo linked study
Liver healthOrgan FunctionSmallCNo linked study
All 7 rated effectsGrouped by health goal, with the publications behind each rating

What is gamma-oryzanol?

Gamma-oryzanol is a mixture of compounds called sterol ferulates obtained from rice-derived material. Research has tested isolated supplements during strength training and gamma-oryzanol added to canola oil in people with type 2 diabetes. Those studies ask different questions and cannot be treated as one interchangeable treatment. 1 2 3 4

Why people take it

Essential Health17.9%
Energy14.1%
Immune Support13.5%
Gut Health9.8%
Fitness8%
Detox7.4%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Questions people ask

Is it an established testosterone booster?

The placebo-controlled trial measuring hormones found no testosterone advantage after nine weeks at 500 mg daily. 2

Were all exercise results negative?

No. A later small trial found better strength in two exercises at 600 mg daily, without changes in body measurements. The studies therefore give mixed results. 2 3

Would I notice the reported anti-inflammatory effect?

The trial measured blood markers, rather than showing symptom relief or fewer disease complications. Its positive marker finding is a reason for further research, not a prediction of how someone will feel. 5

Does an FDA-hosted dossier mean efficacy is approved?

The cited document is a manufacturer’s food-safety submission. It is not an assessment establishing clinical benefit for supplements. 1

Sources