Papaya
Papaya is the fruit of Carica papaya. It supplies vitamin C and fiber, and the unripe fruit is a source of the enzyme papain.
What it is studied for
The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.
What is papaya?
Papaya is the fruit of Carica papaya. It supplies vitamin C and fiber; the unripe fruit is also a source of the protein-splitting enzyme papain. 1
Why people take it
SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.
Questions people ask
Is fresh fruit equivalent to Caricol?
The trial tested a specific preparation at 20 mL daily, so its results cannot be assigned to an ordinary portion of fruit. 2
Has fermented papaya been shown to extend life?
The cited trial measured antioxidant and DNA-damage markers, not lifespan. It cannot answer that question. 3
Is the pregnancy warning based on human trials?
The cited experiment used rats and isolated rat uterine tissue. It distinguishes ripe fruit from latex but does not provide a human pregnancy safety trial. 4
Sources
- Boletín de Frutas y Hortalizas del Convenio INTA-CMCBA No. 65: Papaya INTA and Mercado Central de Buenos Aires; nutrition table sourced to USDA, 2017
- Papaya preparation (Caricol) in digestive disorders Neuro Endocrinology Letters, 2013
- Nutraceutical supplementation: effect of a fermented papaya preparation on redox status and DNA damage in healthy elderly individuals and relationship with GSTM1 genotype Annals of the New York Academy of Sciences, 2006
- Papaya consumption is unsafe in pregnancy: fact or fable? Scientific evaluation using a rat model British Journal of Nutrition, 2002