PQQ
PQQ, or pyrroloquinoline quinone, is a redox compound first found as a cofactor of bacterial enzymes. Foods such as natto, kiwi and parsley contain small amounts.
Also listed as Methoxatin, Pyrroloquinoline Quinone
What it is studied for
The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.
Why is PQQ being studied?
PQQ, short for pyrroloquinoline quinone, increased mitochondrial formation in cultured mouse liver cells. Mitochondria produce cellular energy. This experiment helps explain the research interest, but cannot show that a supplement restores energy in people. 1
Why people take it
SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.
Questions people ask
Does PQQ occur in food?
Yes, in small amounts; EFSA estimated that the proposed supplement intake greatly exceeded background dietary exposure. 2
Does PQQ create more mitochondria in people?
The cited experiment demonstrated this in mouse liver cells, not in people taking capsules. 1
Is the memory finding a dementia treatment result?
No. The cited trial studied cognitive test performance in adults aged 20–65, not treatment of dementia. 3
Ubiquinol