Pterostilbene
Pterostilbene is a plant compound related to resveratrol, found naturally in blueberries and grapes.
Also listed as trans-3 5-dimethoxy-4-hydroxystilbene 3
What happened to cholesterol and blood pressure?
In 80 adults with elevated cholesterol, a six- to eight-week trial compared pterostilbene, a grape-extract combination and placebo. Pterostilbene alone increased LDL by 17.1 mg/dL on average; the combination did not. At 250 mg/day, blood pressure fell by about 8/7 mmHg. These divergent findings do not establish overall cardiovascular benefit. 1
Why is it studied for skin aging?
A review describes cultured human skin cells exposed to UVB. Pterostilbene reduced oxidative stress and DNA damage through antioxidant signaling pathways. This supports further research, but does not demonstrate that oral supplements prevent skin aging in people. 2
Cell findings remain preliminary for human anti-aging claims. 2
Effects by health goal
Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.
Longevity2 effects
No study is linked to this rating.
No study is linked to this rating.
Cognition2 effects
No study is linked to this rating.
Organ Function1 effect
No study is linked to this rating.
Cardiovascular2 effects
No study is linked to this rating.
No study is linked to this rating.
Weight Management1 effect
No study is linked to this rating.
Immune Support1 effect
No study is linked to this rating.
Hair & Skin1 effect
No study is linked to this rating.
Other effects1 effect
No study is linked to this rating.
Sources
- Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trial Evidence-Based Complementary and Alternative Medicine, 2014
- Pterostilbene and resveratrol: Exploring their protective mechanisms against skin photoaging – A scoping review Biochemistry and Biophysics Reports, 2025