Rutin
Rutin is a plant flavonoid, a sugar-bound form of quercetin, found in buckwheat, citrus fruits and the Japanese pagoda tree.
A signal in people with diabetes
Fifty adults with type 2 diabetes were assigned to 1 g rutin daily or placebo for three months. Blood-pressure changes and several antioxidant-enzyme measures favored rutin. This is a reason for larger trials, not an established treatment effect for everyone with high blood pressure. 1
A different trial found no metabolic benefit
Among 87 adults with overweight but without diabetes, 500 mg daily for 12 weeks did not improve the measured response of insulin-producing cells or gut bacterial composition. Rutin was delivered in capsules or enriched yogurt; neither approach produced the hoped-for changes. 2
Absorption does not guarantee protection
In 18 healthy women, six weeks of 500 mg daily increased circulating flavonoids without a clear improvement in antioxidant status. A DNA-oxidation measure improved in both the rutin and placebo groups, so that change cannot be credited to rutin alone. 3
Effects by health goal
Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.
Longevity2 effects
No study is linked to this rating.
No study is linked to this rating.
Essential Health1 effect
No study is linked to this rating.
Cardiovascular2 effects
No study is linked to this rating.
No study is linked to this rating.
Immune Support2 effects
No study is linked to this rating.
No study is linked to this rating.
Bone & Joint1 effect
No study is linked to this rating.
Other effects1 effect
No study is linked to this rating.