5-HTPand Mood Support.
Evidence gradeA
ImpactStrong
Confidencehigh
Imported rating. This grade comes from SuppCo and has not been independently reviewed. It describes research, not a product, and it is not medical advice.
The rating
- Direction
- Favourable
- Rated by
- SuppCo
- Observed
- 28 September 2026
Studies behind it
Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan.E. Turner · Pharmacology & therapeutics2006Stimulatory Effects of L-5-Hydroxytryptophan on Postdexamethasone β-Endorphin Levels in Major DepressionM. Maes · Neuropsychopharmacology1996Tryptophan and 5-hydroxytryptophan for depression.K. Shaw · The Cochrane database of systematic reviews2002