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Botanical

Bitter orange

Bitter orange, Citrus aurantium, is a sour citrus fruit whose peel contains the alkaloid synephrine.

Also listed as P-synephrine, Citrus Aurantium, Synephrine, Citrus aurantium

What happened in the weight-loss trials?

A systematic review pooled 18 articles involving 341 adults. It found no significant weight-loss or body-composition benefit. Small studies and differing products limit the conclusions, but the pooled findings do not support buying synephrine to lose weight. 1

Weight lossNot supported

The pooled human trials did not establish weight loss. 1

Can it improve a workout?

NCCIH describes small exercise studies with inconsistent results; most did not find a benefit. Many products combined bitter orange with other ingredients, making any improvement difficult to attribute to the extract itself. 2

Physical EnergyToo little evidence

The exercise evidence is too inconsistent to establish a dependable benefit. 2

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Weight Management3 effects

Weight lossWeight ManagementSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

MetabolismWeight ManagementSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Appetite & CravingsWeight ManagementSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Energy2 effects

Energy CrashesEnergySmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Physical EnergyEnergySmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cognition2 effects

Mental EnergyCognitionSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Focus And AttentionCognitionNo effectFNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Sources