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Botanical

Carotenoids

Carotenoids are yellow, orange and red plant pigments such as beta-carotene, lutein and lycopene. Some of them can be converted into vitamin A.

A specific use for eye disease

AREDS and AREDS2 combination supplements reduce the relative risk of progression from intermediate to advanced age-related macular degeneration, or AMD, by about 25%. They do not prevent AMD from starting. This evidence concerns people with defined eye disease and complete formulas, not carotenoids in general. 1

Eye HealthSupported

Benefit concerns complete AREDS formulas in selected AMD stages. 1

What does antioxidant research measure?

A review of human intervention studies found that carotenoid mixtures improved some blood measures of antioxidant capacity and lowered triglycerides. Several antioxidant enzymes and HDL cholesterol did not change. These laboratory findings support further research, but do not establish fewer illnesses or longer life. 2

Oxidative stressToo little evidence

Changes in blood markers do not establish disease prevention. 2

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Cardiovascular1 effect

Cholesterol balanceCardiovascularSmallBNo linked study

No study is linked to this rating.

Rated by SuppCo · high confidenceEvidence record

Cognition1 effect

MemoryCognitionSmallBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

All studies

12 publications are linked to Carotenoids, newest first.

Sources

  1. AREDS/AREDS2 Clinical Trials National Eye Institute, 2025