D-Aspartic Acid
D-aspartic acid is the mirror-image form of the amino acid aspartic acid. It occurs naturally in nerve and hormone-producing tissue and is mostly studied for testosterone.
Also listed as D-AA, D-Aspartate, DAA
Does it raise testosterone?
A systematic review found inconsistent human results. An early short study reported higher testosterone, but had important design and analysis weaknesses. Trials in resistance-trained men did not reproduce a consistent increase; one short trial found lower testosterone with 6 g daily. 1
The evidence does not support a dependable testosterone-boosting effect in trained men. Early positive findings remain a research question for other populations, rather than proof that the same response can be expected. 1
Does it add to strength training?
In a 12-week randomized trial, 22 trained men were assigned to 6 g daily or placebo; 19 completed the study. Both groups trained four times weekly. Supplementation did not add gains in strength or muscle size and did not increase total or free testosterone. 2
For this training program and population, D-aspartic acid offered no additional strength benefit over placebo. 2
What about sperm quality?
A 2012 study followed 60 men with impaired semen parameters for 90 days of sodium D-aspartate. Sperm concentration and motility improved compared with their own starting measurements. There was no placebo group, so the study cannot isolate the supplement’s contribution. 3
This is a preliminary fertility signal worth testing in controlled trials, not an established treatment effect. 3
Effects by health goal
Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.
Fertility2 effects
No study is linked to this rating.
No study is linked to this rating.
Sexual Health2 effects
No study is linked to this rating.
No study is linked to this rating.
Fitness2 effects
No study is linked to this rating.
No study is linked to this rating.
Energy1 effect
No study is linked to this rating.
Adverse findings
Ratings where the reported effect was unfavourable.
No study is linked to this rating.