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Sugar

D-Ribose

D-ribose is a naturally occurring simple sugar and a building block of RNA and ATP. It has been studied for symptoms of fibromyalgia and chronic fatigue syndrome.

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

Energy CrashesEnergyModerateBNo linked study
Physical EnergyEnergyModerateBNo linked study
Muscle RecoveryFitnessSmallCNo linked study
Chronic StressStress & MoodSmallCNo linked study
Mental EnergyCognitionSmallCNo linked study
Every rating with its studiesGrouped by health goal, with the publications behind each rating

What is D-ribose?

D-ribose is a naturally occurring sugar studied for symptoms of fibromyalgia and chronic fatigue syndrome. 1

Why people take it

Energy25.2%
Fitness19.4%
Essential Health14.4%
Cardiovascular12.9%
Cognition7%
Immune Support7%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Questions people ask

Is the pilot dose a recommendation?

No. Its 5 g three-times-daily regimen was experimental and came from an uncontrolled study. 1

Can D-ribose cause low blood sugar?

EFSA reported symptomatic hypoglycemia in one fasting participant after 10 g; other glucose reductions were often symptom-free. 2

Sources