L-Glutamine
Glutamine is an amino acid the body produces and also obtains from food. It is especially abundant in muscle and blood.
Also listed as Glutamine
Can it help diarrhea after an infection?
One trial tested 5 g three times daily for eight weeks in post-infectious, diarrhea-predominant irritable bowel syndrome (IBS) with increased intestinal permeability. Among 106 completers, a predefined symptom improvement occurred in 79.6% with glutamine versus 5.8% with placebo. This promising result concerns a selected population, not every cause of bloating or diarrhea. 1
Does it generally improve the gut barrier?
A 2024 meta-analysis found no significant overall improvement in intestinal permeability. Some subgroup analyses were positive, but differences between studies and inconsistent reporting limit dependable conclusions about dose. 2
What about recovery after exercise?
NIH describes a small positive muscle-recovery trial, alongside a weight-training trial that found no strength or lean-mass advantage. These findings do not establish a reliable sports benefit. 3
Small trials leave the size and consistency of any recovery benefit uncertain. 3
Effects by health goal
Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.
Gut Health3 effects
No study is linked to this rating.
Immune Support1 effect
No study is linked to this rating.
Fitness1 effect
No study is linked to this rating.
All studies
3 publications are linked to L-Glutamine, newest first.
Sources
- Dietary Supplements for Exercise and Athletic Performance NIH Office of Dietary Supplements