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Hormone

7-Keto DHEA

7-Keto DHEA is a metabolite of the steroid hormone DHEA that the body forms naturally.

Also listed as 7-ketoDHEA, 7-keto, 7keto, DHEA

Does it produce extra weight loss?

A systematic review found four trials involving 131 participants, lasting one to eight weeks. Two found greater weight loss than placebo and two did not. Participants also followed calorie-restricted diets; some products contained several ingredients. 1

Weight lossMixed

Small, short trials gave conflicting results. 1

A metabolic signal worth separating from weight loss

In a crossover trial completed by 40 overweight adults, seven-day periods of 7-keto-DHEA increased resting metabolic rate by 1.4%, while it fell 3.9% during placebo. Participants were restricting calories. This supports a short-term metabolic effect, not a prediction of sustained weight loss. 2

MetabolismToo little evidence

A brief change in resting energy expenditure needs longer follow-up to establish practical value. 2

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Stress & Mood2 effects

Cortisol stressStress & MoodModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Chronic StressStress & MoodSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Weight Management2 effects

MetabolismWeight ManagementModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Weight lossWeight ManagementModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cognition1 effect

Mental EnergyCognitionNo effectFNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Men's Hormones1 effect

Testosterone SupportMen's HormonesNo effectFNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Sources