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Botanical

Chlorogenic Acid

Chlorogenic acid is a polyphenol found in coffee beans. Roasting reduces it, so concentrated extracts are made from unroasted green coffee beans.

Also listed as Coffee bean extract, Green coffee extract

Does it lower blood pressure?

A 2015 analysis pooled five trials with 364 participants and found average reductions of 4.31 mmHg in systolic pressure and 3.68 mmHg in diastolic pressure. The studies differed considerably, all involved Asian populations, and manufacturers funded them. This is a useful signal requiring independent confirmation. 1

Blood pressureToo little evidence

Small, manufacturer-funded trials reported lower readings; their limitations reduce confidence in a dependable effect. 1

What about weight and blood sugar?

A 2021 review of green-coffee extracts included 15 studies with 637 participants. Average differences favored the extracts by 1.24 kg for weight and 2.21 mg/dL for fasting glucose. HbA1c, a longer-term glucose measure, did not significantly improve. These extract results cannot isolate chlorogenic acid’s contribution. 2

Weight lossToo little evidence

The average weight difference was modest, and the intervention was green-coffee extract. 2

Blood sugarToo little evidence

A small fasting-glucose change did not extend to HbA1c. 2

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Longevity1 effect

Oxidative stressLongevityModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Weight Management3 effects

Blood sugarWeight ManagementModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Weight lossWeight ManagementSmallBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

MetabolismWeight ManagementSmallBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cardiovascular2 effects

Blood pressureCardiovascularModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cholesterol balanceCardiovascularSmallBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Gut Health1 effect

Gut healthModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cognition1 effect

Mental EnergyCognitionSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Other effects1 effect

InflammationModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Sources