Gingerol
Gingerols are pungent constituents of ginger, found alongside related compounds such as shogaols.
A direct test of 6-gingerol
A phase II trial randomized 88 patients receiving chemotherapy to 6-gingerol or placebo alongside standard anti-nausea medicines. The dose was 10 mg twice daily for 12 weeks. Complete response, meaning no vomiting and no rescue medication, occurred in 77% versus 32%. This small trial offers a promising signal, not a replacement for oncology treatment. 1
Inflammation: most human evidence concerns ginger
A 2020 meta-analysis included 25 studies reported in 20 articles. Ginger supplements improved several blood markers of inflammation and oxidative stress, but results varied substantially. These were ginger interventions, so the analysis cannot isolate gingerol’s contribution or turn a blood-marker change into a demonstrated clinical benefit. 2
Why the laboratory findings still matter
The mechanistic review describes experiments involving antioxidant-response pathways and inflammatory signaling. These findings help identify questions for human trials, including whether isolated constituents change immune responses in a useful way; they do not establish fewer infections in supplement users. 3
Effects by health goal
Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.
Longevity2 effects
No study is linked to this rating.
Immune Support1 effect
No study is linked to this rating.
Gut Health1 effect
No study is linked to this rating.
Stress & Mood2 effects
No study is linked to this rating.
No study is linked to this rating.
Other effects1 effect
No study is linked to this rating.
All studies
3 publications are linked to Gingerol, newest first.