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Botanical

Grape

Grapes are the fruit of the grapevine, Vitis vinifera. Supplements use extracts of the fruit, skin, seeds or leaves.

Also listed as Grape Extract, Grape Fruit, Grape Fruit Extract, Grape fruit skin

LongevityImmune SupportCognitionCardiovascular

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

Oxidative stressLongevityModerateA3 studies
Cellular health & agingLongevityModerateBNo linked study
Immune SupportModerateBNo linked study
MemoryCognitionSmallBNo linked study
Cholesterol balanceCardiovascularSmallBNo linked study
Blood pressureCardiovascularSmallBNo linked study
Every rating with its studiesGrouped by health goal, with the publications behind each rating

Are studies testing the grapes in my fruit bowl?

Not always. A cholesterol review combined studies of whole-grape powder or pomace, juice, seed extract and skin extract. That range matters when deciding how closely a study resembles eating fresh grapes. 1

Key studies

The most recent publications linked to Grape's ratings.

Effects of grape products on inflammation and oxidative stress: A systematic review and meta‐analysis of randomized controlled trials2021Grape polyphenols supplementation for exercise-induced oxidative stress2021Grape polyphenols exert a cardioprotective effect in pre- and postmenopausal women by lowering plasma lipids and reducing oxidative stress.2005

Why people take it

Immune Support18.8%
Essential Health15.8%
Energy12.8%
Longevity9.1%
Cardiovascular8.2%
Detox7.2%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Questions people ask

Is grape juice interchangeable with whole grapes in research?

No single result covers every preparation: the cholesterol review included juice, powders, seed extracts and skin extract. 1

How much fiber is in grapes?

The Canadian table lists 1.2 g per 100 g of fresh grapes. 2

Can toddlers eat whole grapes?

The NHS recommends cutting grapes into quarters and supervising young children while they eat. 3

Sources