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Bacteria

Lactobacillus salivarius

Lactobacillus salivarius, now named Ligilactobacillus salivarius, is a lactic acid bacterium that naturally lives in the human mouth and gut.

Gut HealthImmune Support

What it is studied for

The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.

Gut healthModerateBNo linked study
DiarrheaModerateBNo linked study
ConstipationModerateBNo linked study
Bloating & gas reliefGut HealthModerateBNo linked study
Digestive sensitivityGut HealthModerateBNo linked study
Immune SupportModerateBNo linked study
All 8 rated effectsGrouped by health goal, with the publications behind each rating

Which L. salivarius are you looking at?

The strain code matters as much as the species name: probiotic findings cannot automatically be shared across strains. PS2 has been studied for mastitis prevention, while UCC4331 was tested in people with irritable bowel syndrome. 1 2 3

Why people take it

Gut Health26.3%
Immune Support26%
Essential Health23.9%
Detox10.7%
Energy5.3%
Women's Hormones2.5%

SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.

Questions people ask

Is PS2 interchangeable with UCC4331?

No. These are distinct strains studied for different outcomes; a result for one does not establish benefit from the other. 1 2 3

Do fermented foods provide the same benefit?

Not necessarily. A fermented food is not automatically a probiotic with a demonstrated health benefit. 1

Does the mastitis trial prove that all L. salivarius products work?

No. It supports further consideration of PS2 in the studied prevention setting, not every product carrying the species name. 3

Is a higher CFU count better?

Not by itself. The tested strain and intended use matter more than choosing the largest number. 1

Sources

  1. Probiotics: Fact Sheet for Consumers NIH Office of Dietary Supplements