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Enzyme

Ubiquinol

Ubiquinol is the reduced form of coenzyme Q10, a fat-soluble compound the body makes itself and uses for energy production in mitochondria.

What the fatigue trial measured

A 12-week placebo-controlled trial analyzed 62 adults receiving 100 mg or 150 mg ubiquinol daily, or placebo. Both active groups reported less fatigue and sleepiness after mental tasks. The participants had mild fatigue lasting one to six months; the result does not establish treatment for chronic fatigue syndromes. 1

A blood-test finding, not disease prevention

In a German study, 53 healthy men received 150 mg daily for 14 days. The enzyme GGT, investigated as an indirect oxidative-stress marker, decreased. There was no placebo group in this supplementation comparison, and another liver enzyme did not change. These findings leave disease prevention and longer-term benefit unanswered. 2

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Energy2 effects

Physical EnergyEnergyModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Energy CrashesEnergyModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cardiovascular2 effects

Cholesterol balanceCardiovascularSmallBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Blood pressureCardiovascularSmallBNo linked study

No study is linked to this rating.

Rated by SuppCo · high confidenceEvidence record

All studies

3 publications are linked to Ubiquinol, newest first.

Sources