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Urolithin A

Urolithin A is a compound that gut bacteria make from ellagitannins in foods such as pomegranates, walnuts and berries.

An endurance signal, with an important negative result

In 66 adults aged 65–90, 1,000 mg daily for four months improved repeated hand and leg contractions at two months versus placebo. However, the main outcomes, six-minute walking distance and maximal muscle energy production, did not improve significantly versus placebo. The study had manufacturer involvement. 1

What does mitochondrial research mean?

Mitochondria help cells produce usable energy. Urolithin A is studied for mitophagy, the removal of damaged mitochondria, with encouraging animal findings and changes in human molecular markers. Such changes are research clues, not measurements of longer human life. 1 2

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Fitness2 effects

Muscle RecoveryFitnessModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Endurance and staminaFitnessModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Energy1 effect

Physical EnergyEnergyModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cognition1 effect

MemoryCognitionSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Other effects1 effect

InflammationModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

All studies

3 publications are linked to Urolithin A, newest first.

Sources