Saffronand Chronic Stress.
Evidence gradeA
ImpactModerate
Confidencehigh
Imported rating. This grade comes from SuppCo and has not been independently reviewed. It describes research, not a product, and it is not medical advice.
The rating
- Direction
- Favourable
- Rated by
- SuppCo
- Observed
- 28 September 2026
Studies behind it
Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical TrialP. Jackson · Frontiers in Nutrition2021Stress-induced alterations in hippocampal BDNF in the pathophysiology of Major Depressive Disorder and the antidepressant effect of saffron.Rachel Philpotts · Journal of Affective Disorders Reports2023Effect of saffron supplementation on symptoms of depression and anxiety: a systematic review and meta-analysis.W. Marx · Nutrition reviews2019