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Botanical

Chaste tree

Chaste tree (Vitex agnus-castus) is a Mediterranean shrub whose dried fruit, called chasteberry, is used in herbal preparations, mainly for premenstrual symptoms.

Also listed as Chaste Tree Berry, Chasteberry, Vitex Agnus-castus, Chaste Tree Fruit

A positive PMS finding with a product boundary

A 2019 meta-analysis retained three placebo-controlled trials of clearly described extracts from 21 candidate trials. Symptoms improved more often with the extracts, but poor reporting excluded most trials. The evidence supports particular preparations rather than every product labeled vitex. 1

Menstruation SupportMixed

Positive PMS results apply to characterized extracts; generalization is limited. 1

A proposed mechanism

Laboratory findings suggest effects on brain hormone-regulating pathways and prolactin production. EMA notes that the mechanism is not fully understood. 2

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Women's Hormones4 effects

Menstruation SupportWomen's HormonesStrongA3 studies
Estrogen BalanceWomen's HormonesModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

OvulationFertility · Women's HormonesModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Estrogen SupportWomen's HormonesSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Fertility1 effect

Pregnancy PrepFertilityModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Hair & Skin1 effect

Clear SkinHair & SkinSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Sexual Health1 effect

Female LibidoSexual HealthSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Stress & Mood2 effects

Mood SupportStress & MoodSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Chronic StressStress & MoodSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

All studies

3 publications are linked to Chaste tree, newest first.

Sources

  1. Agni casti fructus European Medicines Agency