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Botanical

Jiaogulan

Jiaogulan, Gynostemma pentaphyllum, is a climbing vine of the cucumber family from Asia. It contains saponins called gypenosides.

Also listed as Southern Ginseng, Jiao Gu-lan, Giao-Co-Lam (Tea), Gynostemma Pentaphyllum

A promising glucose signal in a small group

A 12-week trial in 24 adults with untreated type 2 diabetes found better blood-glucose measurements with 6 g of jiaogulan tea daily than with placebo tea. Both groups received diet and exercise guidance. A separate small trial found additional glucose lowering when an extract was added to gliclazide. These findings support further clinical testing, not self-directed replacement of diabetes care. 1 2

MetabolismToo little evidence

Small diabetes trials found improved glucose control; applicability beyond those patients is uncertain. 1 2

Cholesterol findings need a careful comparison

A review of 22 trials found possible benefits when jiaogulan was added to lipid-lowering treatment. Most trials had methodological concerns. Comparisons with medicines were too uncertain to establish equivalence, and LDL cholesterol outcomes favored statins or fenofibrate over jiaogulan. 3

Cholesterol balanceMixed

Adjunctive results were encouraging, but quality and comparator differences limit conclusions. 3

One anxiety measure improved, others did not

In 72 otherwise healthy adults with chronic stress, 400 mg of leaf extract daily for eight weeks improved a measure of anxiety proneness. Several other anxiety scales and physiological measures did not differ significantly from placebo. This is a specific preliminary result, not evidence that jiaogulan treats an anxiety disorder. 4

StressToo little evidence

One questionnaire outcome improved in a short trial, while several others did not. 4

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

Immune Support1 effect

Immune SupportModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cardiovascular2 effects

Blood pressureCardiovascularModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Cholesterol balanceCardiovascularModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Weight Management1 effect

MetabolismWeight ManagementModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Longevity1 effect

Oxidative stressLongevityModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Stress & Mood2 effects

StressStress & MoodSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Mood SupportStress & MoodSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · low confidenceEvidence record

Cognition1 effect

Mental EnergyCognitionSmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Energy1 effect

Energy CrashesEnergySmallCNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Other effects1 effect

InflammationModerateBNo linked study

No study is linked to this rating.

Rated by SuppCo · medium confidenceEvidence record

Sources