Sodium Bicarbonate
Sodium bicarbonate is baking soda, an alkaline salt of sodium used in cooking, as an antacid and in sports research.
Also listed as Baking Soda, Bicarb, Bicarbonate
What it is studied for
The strongest rated effects first. Bars show the size of the effect, the letter grades the evidence, and each rating lists the studies behind it.
Why do people take it?
Sodium bicarbonate is used as an antacid and is prescribed for certain acid–base disorders. Sports research examines a separate use: buffering acid during intense exercise. 1 2
What does acidosis mean here?
Metabolic acidosis is excess acid in the blood, sometimes associated with advanced kidney disease. A blood test helps establish the problem. 3
Key studies
The most recent publications linked to Sodium Bicarbonate's ratings.
Why people take it
SuppCo community snapshot, 2026-09-28. Reasons for use are not evidence that it works.
Questions people ask
Will it increase maximum strength?
The cited meta-analysis found no improvement in muscular strength, although endurance improved modestly. 4
Is a larger sports dose better?
The ISSN review found more side effects at 0.4–0.5 g/kg without a clear additional benefit. 2
Can I diagnose acidosis from how I feel?
Kidney-related metabolic acidosis is assessed with blood testing and clinical evaluation. 3
Does the kidney research apply to healthy people?
The cited trials enrolled people with chronic kidney disease; they do not establish preventive benefits in healthy kidneys. 5
Can I take it with my regular medicines?
MedlinePlus advises at least two hours of separation; discuss the combination with your clinician or pharmacist. 1
Sources
- Sodium Bicarbonate MedlinePlus
- International Society of Sports Nutrition position stand: sodium bicarbonate and exercise performance Journal of the International Society of Sports Nutrition, 2021
- Metabolic acidosis National Kidney Foundation, 2024
- A Systematic Review and Meta-Analysis on Effects of Bicarbonate Therapy on Kidney Outcomes Kidney International Reports, 2021 · Study record