Tryptophanand Sleep Onset.
Evidence gradeA
ImpactModerate
Confidencehigh
Imported rating. This grade comes from SuppCo and has not been independently reviewed. It describes research, not a product, and it is not medical advice.
The rating
- Direction
- Favourable
- Rated by
- SuppCo
- Observed
- 28 September 2026
Studies behind it
The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression.W. W. Loh · Nutrition reviews2021Evaluation of l-tryptophan for treatment of insomnia: A reviewD. Schneider-Helmert · Psychopharmacology2004The Impact of Tryptophan Supplementation on Sleep Quality: A Systematic Review, Meta-Analysis and Meta-RegressionC. Sutanto2021