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Astaxanthin

Astaxanthin is a red carotenoid pigment produced by the microalga Haematococcus pluvialis. It reaches crustaceans and salmon through their food and colors them red.

Also listed as Cardax

Does it improve skin moisture or wrinkles?

A 2021 meta-analysis found improvements in skin moisture and elasticity with oral astaxanthin, but no statistically clear reduction in wrinkle depth. A separate clinical review highlighted small samples, mostly healthy Japanese women, and frequent commercial funding. 1 2

Skin textureMixed

Moisture and elasticity results are promising, but the evidence has important limitations. 1 2

Anti-aging SkinToo little evidence

The pooled wrinkle-depth result did not establish a benefit. 1 2

Can it lower blood sugar or blood pressure?

A 2022 review in adults at risk of metabolic syndrome found no clear overall reductions in fasting blood glucose, body mass index or diastolic blood pressure, the lower reading. The result for systolic pressure, the upper reading, was borderline, so it does not establish a dependable treatment effect. 3

Blood sugarToo little evidence

The pooled fasting-glucose result did not show a significant benefit. 3

Blood pressureMixed

Results differed by blood-pressure measure, with no clear diastolic benefit. 3

What about fatigue, thinking and exercise?

A 2024 review included 11 trials with 346 healthy participants. Fatigue findings came from only two studies; cognitive accuracy results were borderline and reaction time did not improve significantly. Exercise performance showed a positive pooled result, but the authors called for larger studies. 4

Does it prevent eye disease?

The German consumer advice centers consider evidence for eye-health claims inadequate. They recommend discussing supplements with an eye-care practice when an eye disease is already present. 5

Effects by health goal

Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.

All studies

29 publications are linked to Astaxanthin, newest first.

Astaxanthin Supplementation as a Potential Strategy for Enhancing Mitochondrial Adaptations in the Endurance Athlete: An Invited Review2024Effect of astaxanthin on physical activity factors, lipid profile, inflammatory markers, and antioxidants indices in athletic men: A systematic review and meta-analysis2024Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis2024Effects of Astaxanthin Supplementation on Fatigue, Motor Function and Cognition: A Meta-Analysis of Randomized Controlled Trials2024The Effects of Astaxanthin on Cognitive Function and Neurodegeneration in Humans: A Critical Review2024Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins2023The Role of Astaxanthin as a Nutraceutical in Health and Age-Related Conditions2022Health benefits of astaxanthin against age-related diseases of multiple organs: A comprehensive review2022Benefits and Safety of Astaxanthin in the Treatment of Mild-To-Moderate Dry Eye Disease2022Effects of diet containing astaxanthin on visual function in healthy individuals: a randomized, double-blind, placebo-controlled, parallel study2022Astaxanthin Influence on Health Outcomes of Adults at Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis2022Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.2021Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Ageing2021The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes2021Anti-inflammatory action of astaxanthin and its use in the treatment of various diseases.2021Antioxidant and anti-inflammatory mechanisms of action of astaxanthin in cardiovascular diseases (Review)2020Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies2020Clinical Applications of Astaxanthin in the Treatment of Ocular Diseases: Emerging Insights2020The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials.2020Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review2018

Sources

  1. Astaxanthin für den guten Durchblick? Verbraucherzentrale Baden-Württemberg