Medium-chain Triglycerides
Medium-chain triglycerides (MCTs) are fats built from fatty acids with 6 to 12 carbon atoms. They occur in coconut and palm kernel oil, and MCT oil is made from them.
Also listed as MCTs, MCT oil, medium-chain fatty acids
Can MCT oil help with weight loss?
A meta-analysis of 11 trials found about 0.69 kg more weight loss when MCTs replaced long-chain fats. Evidence quality was low to moderate. This tests substitution, not adding oil on top of the usual diet. 1
What about cognition?
A 2023 meta-analysis in mild cognitive impairment or Alzheimer’s disease found improvement in overall cognition, but not separate memory, language, or attention measures. The signal concerns affected patients, not established cognitive enhancement in healthy people. 2
MCT-derived ketones are being investigated as an alternative brain fuel when glucose metabolism is impaired; that mechanism is a rationale, not proof of clinical benefit. 2
Does it improve cholesterol?
Across seven trials, MCT oil did not change LDL cholesterol overall and slightly increased triglycerides. Against mainly unsaturated oils, it increased LDL. The comparison oil changes the interpretation. 3
Effects by health goal
Open an effect to see the studies behind its rating. Bars show the size of the effect; the letter grades the evidence.
Energy2 effects
No study is linked to this rating.
No study is linked to this rating.
Gut Health1 effect
No study is linked to this rating.
Longevity1 effect
No study is linked to this rating.
Weight Management2 effects
No study is linked to this rating.
No study is linked to this rating.
Cognition2 effects
No study is linked to this rating.
Cardiovascular1 effect
No study is linked to this rating.
Other effects1 effect
No study is linked to this rating.
Sources
- Dietary medium-chain triacylglycerols versus long-chain triacylglycerols for body composition in adults: systematic review and meta-analysis of randomized controlled trials Journal of the American College of Nutrition, 2015
- The Effects of Medium Chain Triglyceride for Alzheimer's Disease Related Cognitive Impairment: A Systematic Review and Meta-Analysis Journal of Alzheimer's Disease, 2023
- Medium-Chain Triglyceride Oil and Blood Lipids: A Systematic Review and Meta-Analysis of Randomized Trials Journal of Nutrition, 2021